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Results: 6
Network regression analysis in transcriptome-wide association studies.
BACKGROUND: Transcriptome-wide association studies (TWASs) have shown great promise in interpreting the findings from genome-wide association studies (GWASs) and exploring the disease mechanisms, by integrating GWAS and eQTL...
Identifying the parametric occurrence of multiple steady states for some biological networks
Russell Bradford, James H. Davenport, Matthew England, Hassan Errami, Vladimir Gerdt, Dima Grigoriev, Charles Hoyt, Marek Košta, Ovidiu Radulescu, Thomas Sturm, Andreas Weber
May 01, 2020
We consider a problem from biological network analysis of determining regions in a parameter space over which there are multiple steady states for positive real values of variables and parameters. We describe multiple...
PMINR
Weiqiang Lin, Jiadong Ji, Yuchen Zhu, Mingzhuo Li, Jinghua Zhao, Fuzhong Xue, Zhongshang Yuan
Oct 29, 2020
Complex diseases are believed to be the consequence of intracellular network(s) involving a range of factors. An improved understanding of a disease-predisposing biological network could lead to better identification of genes...
Identifying the parametric occurrence of multiple steady states for some biological networks
Russell Bradford, James H. Davenport, Matthew England, Hassan Errami, Vladimir Gerdt, Dima Grigoriev, Charles Hoyt, Marek Košta, Ovidiu Radulescu, Thomas Sturm, Andreas Weber
May 01, 2020
We consider a problem from biological network analysis of determining regions in a parameter space over which there are multiple steady states for positive real values of variables and parameters. We describe multiple...
Topological sensitivity analysis for systems biology.
Mathematical models of natural systems are abstractions of much more complicated processes. Developing informative and realistic models of such systems typically involves suitable statistical inference methods, domain expertise...
Network regression analysis in transcriptome-wide association studies.
BACKGROUND: Transcriptome-wide association studies (TWASs) have shown great promise in interpreting the findings from genome-wide association studies (GWASs) and exploring the disease mechanisms, by integrating GWAS and eQTL...