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Role of THRB, ARG1, and ADRB2 Genetic Variants on Bronchodilators Response in Asthmatic Children.
Alessandra Scaparrotta, Marica Franzago, Maria Loredana Marcovecchio, Sabrina Di Pillo, Francesco Chiarelli, Angelika Mohn, Liborio Stuppia
Feb 12, 2019
Background: An interindividual variability in response to short-acting bronchodilator drugs (short-acting inhaled β2-agonists, SABA) exists and this is linked in part to genetic factors. The aim of this study was to verify the...
Asthma bronchodilator response children Genetic variants Pharmacogenetics Administration Inhalation Adrenergic beta-2 Receptor Agonists Arginase Asthma Bronchodilator Agents Child Female Forced Expiratory Volume Genes erbA genetic variation Genotype Humans Male Polymorphism Single Nucleotide Prospective Studies Receptors Adrenergic beta-2 Spirometry