Begin your search of the AGOSR Open Access Database

Search

Reset
Results: 1
Cover Image for Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers. View Article
Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers.
Adriana Ordóñez, Heather P Harding, Stefan J Marciniak, David Ron
Apr 28, 2021
Circulating polymers of α1-antitrypsin (α1AT) are neutrophil chemo-attractants and contribute to inflammation, yet cellular factors affecting their secretion remain obscure. We report on a genome-wide CRISPR-Cas9 screen for...
CHO CRISPR-Cas9 library CHO Cells ERGIC-53 LMAN1 SURF4 cargo receptors Endoplasmic Reticulum genome-wide CRISPR-Cas9 screen polymer trafficking α1-Antitrypsin Endoplasmic Reticulum Humans Polymers alpha 1-Antitrypsin
Published by: