Stem Cell Proliferation Is Kept in Check by the Chromatin Regulators Kismet/CHD7/CHD8 and Trr/MLL3/4.
Louis Gervais,
Marius van den Beek,
Manon Josserand,
Jérémy Sallé,
Marine Stefanutti,
Carolina N Perdigoto,
Patricia Skorski,
Khallil Mazouni,
Owen J Marshall,
Andrea H Brand,
François Schweisguth,
Allison J Bardin
Apr 26, 2019
Chromatin remodeling accompanies differentiation, however, its role in self-renewal is less well understood. We report that in Drosophila, the chromatin remodeler Kismet/CHD7/CHD8 limits intestinal stem cell (ISC) number and...