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Actin-capping protein regulates actomyosin contractility to maintain germline architecture in C. elegans.
A theory that predicts behaviors of disordered cytoskeletal networks.
Morphogenesis in animal tissues is largely driven by actomyosin networks, through tensions generated by an active contractile process. Although the network components and their properties are known, and networks can be...
A disassembly-driven mechanism explains F-actin-mediated chromosome transport in starfish oocytes.
While contraction of sarcomeric actomyosin assemblies is well understood, this is not the case for disordered networks of actin filaments (F-actin) driving diverse essential processes in animal cells. For example, at the onset...
The actin cortex at a glance.
Precisely controlled cell deformations are key to cell migration, division and tissue morphogenesis, and have been implicated in cell differentiation during development, as well as cancer progression. In animal cells, shape...