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Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.
Kapil Gupta, Aleksandra A Watson, Tiago Baptista, Elisabeth Scheer, Anna L Chambers, Christine Koehler, Juan Zou, Ima Obong-Ebong, Eaazhisai Kandiah, Arturo Temblador, Adam Round, Eric Forest, Petr Man, Christoph Bieniossek, Ernest D Laue, Edward A Lemke, Juri Rappsilber, Carol V Robinson, Didier Devys, Làszlò Tora, Imre Berger
Jan 24, 2018
General transcription factor TFIID is a key component of RNA polymerase II transcription initiation. Human TFIID is a megadalton-sized complex comprising TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). TBP binds...
S. cerevisiae TBP associated factors TFIID Biochemistry biophysics core promoter DNA Gene regulation histone fold domain human structural biology Transcription Factors Crystallography X-Ray DNA Histone Acetyltransferases Humans Mass Spectrometry Promoter Regions Genetic Protein Binding Protein Conformation Protein Interaction Mapping TATA-Binding Protein Associated Factors TATA-Box Binding Protein Transcription Factor TFIID