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Chicken cGAS Senses Fowlpox Virus Infection and Regulates Macrophage Effector Functions.
Marisa Oliveira, Damaris Ribeiro Rodrigues, Vanaique Guillory, Emmanuel Kut, Efstathios S Giotis, Michael A Skinner, Rodrigo Guabiraba, Clare E Bryant, Brian J Ferguson
Jan 06, 2021
The anti-viral immune response is dependent on the ability of infected cells to sense foreign nucleic acids. In multiple species, the pattern recognition receptor (PRR) cyclic GMP-AMP synthase (cGAS) senses viral DNA as an...
DNA chicken cyclic GMP-AMP synthase fowlpox MACROPHAGES pattern recognition receptor stimulator of interferon genes Animals Cell Line Chickens DNA Viruses DNA Viral Fowlpox Fowlpox virus Histocompatibility Antigens Class II Interferon Type I MACROPHAGES Membrane Proteins Nucleotides Cyclic Signal Transduction
Chicken cGAS Senses Fowlpox Virus Infection and Regulates Macrophage Effector Functions
Marisa Oliveira, Damaris Ribeiro Rodrigues, Vanaique Guillory, Emmanuel Kut, Efstathios S. Giotis, Michael A. Skinner, Rodrigo Guabiraba, Clare E. Bryant, Brian J. Ferguson
Feb 15, 2021
The anti-viral immune response is dependent on the ability of infected cells to sense foreign nucleic acids. In multiple species, the pattern recognition receptor (PRR) cyclic GMP-AMP synthase (cGAS) senses viral DNA as an...