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OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE)
James P Sheppard, Jenni Burt, Mark Lown, Eleanor Temple, John Benson, Gary A Ford, Carl Heneghan, FD Richard Hobbs, Sue Jowett, Paul Little, Jonathan Mant, Jill Mollison, Alecia Nickless, Emma Ogburn, Rupert Payne, Marney Williams, Ly-Mee Yu, Richard J McManus
Nov 15, 2018
INTRODUCTION: Recent evidence suggests that larger blood pressure reductions and multiple antihypertensive drugs may be harmful in older people, particularly frail individuals with polypharmacy and multimorbidity. However, there...
antihypertensive cardiovascular disease de-prescribing frailty Multi-morbidity Aged Blood Pressure Determination Deprescriptions Female Humans Hypertension Male multimorbidity Outcome and Process Assessment Health Care Patient Care Management Polypharmacy Primary Health Care Quality of life Severity of Illness Index