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Designing an oncology clinical program is more challenging than designing a single study. The standard approaches have been proven to be not very successful during the last decade; the failure rate of Phase 2 and Phase 3...

Adaptive trial design decision analysis expected net present value group sequential design modeling and simulation optimizing drug development Probability of success

Hypertension cost-effectiveness decision analysis decision model self-management Age Factors Aged Aged 80 and over Antihypertensive Agents blood pressure Cost-Benefit Analysis Decision Support Techniques Drug Costs Female Humans Hypertension Male Markov Chains Models Economic Process Assessment Health Care Quality-Adjusted Life Years Self Care Time Factors Treatment Outcome United Kingdom

A neglected area of scenario planning is the provision of support for strategic decisions that involve multiple attributes. When the number of scenarios and attributes is large, conventional multiattribute decision analysis...

scenario planning decision analysis multiattribute decisions SMART

We consider portfolio decision problems with positive interactions between projects. Exact solutions to this problem require that all interactions are assessed, requiring time, expertise and effort that may not always be...

Decision Making decision analysis portfolio selection Heuristics behavioural decision making

We examine the situation where a decision maker is considering investing in a number of projects with uncertain revenues. Before making a decision, the investor has the option to purchase data which carry information about the...

decision analysis Generalised linear mixed model Laplace approximation sampling design value of information /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being

We consider portfolio decision problems with positive interactions between projects. Exact solutions to this problem require that all interactions are assessed, requiring time, expertise and effort that may not always be...

Decision Making decision analysis portfolio selection Heuristics behavioural decision making

This study presents a novel integrated decision model for optimal planning oil palm value chains (OPVC) incorporating decisions to minimise biodiversity losses by limiting the expansion of oil palm plantations as needed and...

decision analysis Environment-food-energy-water nexus Fuzzy analytic hierarchy process Oil palm value chains Optimisation process systems engineering Sustainable palm oil /dk/atira/pure/subjectarea/asjc/1300/1305 name=Biotechnology /dk/atira/pure/subjectarea/asjc/1100/1106 name=Food Science /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering

BACKGROUND AND OBJECTIVE: Advanced analytic methods for synthesizing evidence about complex interventions continue to be developed. In this paper, we emphasize that the specific research question posed in the review should be...

Bayesian analysis decision analysis Finite mixture models Meta-Analysis meta-regression qualitative synthesis Systematic review Bayes Theorem Decision Making Evidence-Based Medicine Finite element analysis Guidelines as Topic Humans Meta-Analysis as Topic qualitative research Research Design Review Literature as Topic

We examine the situation where a decision maker is considering investing in a number of projects with uncertain revenues. Before making a decision, the investor has the option to purchase data which carry information about the...

decision analysis Generalised linear mixed model Laplace approximation sampling design value of information /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being

Hypertension blood pressure target cost effectiveness decision analysis decision model stroke transient ischaemic attack Aged Aged 80 and over Antihypertensive Agents blood pressure Costs and Cost Analysis Decision Support Techniques England Female Humans Hypertension Incidence Ischemic Attack Transient Male Middle Aged Models Economic Primary Health Care Prognosis Quality-Adjusted Life Years stroke Survival Rate

This paper provides a two-stage decision framework in which two or more parties exercise a jointly held real option. We show that a single party’s timing decision is always socially efficient if it precedes bargaining on the...

decision analysis Investment timing Real options Nash bargaining solution Agency problem

This paper provides a two-stage decision framework in which two or more parties exercise a jointly held real option. We show that a single party’s timing decision is always socially efficient if it precedes bargaining on the...

decision analysis Investment timing Real options Nash bargaining solution Agency problem

Conservation decisions are challenging, not only because they often involve difficult conflicts among outcomes that people value, but because our understanding of the natural world and our effects on it is fraught with...

adaptive management Biodiversity decision analysis decision theory Ecology funding reporting standards research prioritisation uncertainty Animals Biodiversity Conservation of Natural Resources Decision Making Decision Support Techniques Ecology Humans Population Density uncertainty

Designing an oncology clinical program is more challenging than designing a single study. The standard approaches have been proven to be not very successful during the last decade; the failure rate of Phase 2 and Phase 3...

Adaptive trial design decision analysis expected net present value group sequential design modeling and simulation optimizing drug development Probability of success

A neglected area of scenario planning is the provision of support for strategic decisions that involve multiple attributes. When the number of scenarios and attributes is large, conventional multiattribute decision analysis...

scenario planning decision analysis multiattribute decisions SMART

This study presents a novel integrated decision model for optimal planning oil palm value chains (OPVC) incorporating decisions to minimise biodiversity losses by limiting the expansion of oil palm plantations as needed and...

decision analysis Environment-food-energy-water nexus Fuzzy analytic hierarchy process Oil palm value chains Optimisation process systems engineering Sustainable palm oil /dk/atira/pure/subjectarea/asjc/1300/1305 name=Biotechnology /dk/atira/pure/subjectarea/asjc/1100/1106 name=Food Science /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering