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Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
Kristin V. Tarbell
,
Lucine Petit Francis
,
Xiaopan Zuo
Jan 01, 0001
Most treatments that prevent autoimmune diabetes in nonobese diabetic (NOD) mice require intervention at early pathogenic stages, when insulitis is first developing. We tested whether dendritic cell (DC)-expanded, islet...
dendritic cel
ldiabetes mellitus
Insulin
insulitis
pancreas islet beta cell
regulatory T lymphocyte
Published by:
Rockefeller University