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Allograft rejection is associated with development of functional IgE specific for donor MHC antigens.
Andreas M Farkas, Ulrike Baranyi, Georg A Böhmig, Lukas Unger, Stefan Hopf, Markus Wahrmann, Heinz Regele, Benedikt Mahr, Christoph Schwarz, Karin Hock, Nina Pilat, Ivan Kristo, Jasmin Mraz, Christian Lupinek, Josef Thalhamer, Gregor Bond, Lorenz Kuessel, Elizabeth Wlodek, Jack Martin, Menna Clatworthy, Gavin Pettigrew, Rudolf Valenta, Thomas Wekerle
Dec 17, 2018
BACKGROUND: Donor-specific antibodies of the IgG isotype are measured routinely for diagnostic purposes in renal transplant recipients and are associated with antibody-mediated rejection and long-term graft loss. OBJECTIVE: This...
IgE Transplantation alloreactivity donor-specific antibodies humoral rejection immunology Allografts Animals Female Graft Rejection Heart Transplantation Histocompatibility Antigens Class I Histocompatibility Antigens Class II Humans Immunoglobulin E Immunoglobulin G Kidney Transplantation Male Mice Mice Inbred BALB C Skin Transplantation