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Selective D3 receptor antagonism modulates neural response during negative emotional processing in substance dependence.
Selective D3 receptor antagonism modulates neural response during negative emotional processing in substance dependence.
Ioanna A Vamvakopoulou, Leon Fonville, Alexandra Hayes, John McGonigle, Rebecca Elliott, Karen D Ersche, Remy Flechais, Csaba Orban, Anna Murphy, Dana G Smith, John Suckling, Eleanor M Taylor, Bill Deakin, Trevor W Robbins, David J Nutt, Anne R Lingford-Hughes, Louise M Paterson
Dec 08, 2022
INTRODUCTION: Negative affective states contribute to the chronic-relapsing nature of addiction. Mesolimbic dopamine D3 receptors are well placed to modulate emotion and are dysregulated in substance dependence. Selective...