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A non-canonical ESCRT pathway, including histidine domain phosphotyrosine phosphatase (HD-PTP), is used for down-regulation of virally ubiquitinated MHC class I.
Michael DJ Parkinson
,
Siân C Piper
,
Nicholas A Bright
,
Jennifer L Evans
,
Jessica M Boname
,
Katherine Bowers
,
Paul J Lehner
,
J Paul Luzio
Jul 30, 2015
Endocytosis
endosomal sorting complex required for transport (ESCRT)
histidine domain phosphotyrosine phosphatase (HD-PTP)
histidine-domain protein tyrosine phosphatase non-receptor type 23 (PTPN23)
lysosome
ubiquitination (ubiquitylation)
Down-Regulation
Endosomal Sorting Complexes Required for Transport
HeLa Cells
Herpesvirus 8
Human
Histocompatibility Antigens Class I
Humans
Protein Tyrosine Phosphatases
Non-Receptor
Ubiquitination
Viral Proteins
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