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Peripheral innate immune and bacterial signals relate to clinical heterogeneity in Parkinson's disease.
Ruwani S Wijeyekoon, Deborah Kronenberg-Versteeg, Kirsten M Scott, Shaista Hayat, Wei-Li Kuan, Jonathan R Evans, David P Breen, Gemma Cummins, Joanne L Jones, Menna R Clatworthy, R Andres Floto, Roger A Barker, Caroline H Williams-Gray
Feb 03, 2020
The innate immune system is implicated in Parkinson's disease (PD), but peripheral in-vivo clinical evidence of the components and driving mechanisms involved and their relationship with clinical heterogeneity and progression to...
The endotoxin hypothesis of neurodegeneration
Guy C. Brown
Sep 12, 2020
Abstract: The endotoxin hypothesis of neurodegeneration is the hypothesis that endotoxin causes or contributes to neurodegeneration. Endotoxin is a lipopolysaccharide (LPS), constituting much of the outer membrane of...