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Results: 22
Fetal Growth and the Risk of Spontaneous Preterm Birth in a Prospective Cohort Study of Nulliparous Women.
Multiple Micronutrient Supplementation during Pregnancy and Increased Birth Weight and Skinfold Thicknesses in the Offspring
Deletion of the Imprinted Phlda2 Gene Increases Placental Passive Permeability in the Mouse
Emily Angiolini, Ionel Sandovici, Philip M. Coan, Graham J. Burton, Colin P. Sibley, Abigail L. Fowden, Miguel Constância
Apr 26, 2021
Genomic imprinting, an epigenetic phenomenon that causes the expression of a small set of genes in a parent-of-origin-specific manner, is thought to have co-evolved with placentation. Many imprinted genes are expressed in the...
The relationship between human placental morphometry and ultrasonic measurements of utero-placental blood flow and fetal growth.
Exploring the causes and consequences of maternal metabolic maladaptations during pregnancy
Pregnancy is a remarkable physiological state, during which the metabolic system of the mother adapts to ensure that nutrients are made available for transfer to the fetus for growth and development. Adaptations of maternal...
Associations between Maternal Iron Supplementation in Pregnancy and Changes in Offspring Size at Birth Reflect Those of Multiple Micronutrient Supplementation
It was previously observed that in a population of a high-income country, dietary multiple micronutrient supplementation in pregnancy was associated with an increased risk of gestational diabetes (GDM) and increased offspring...
Slowing of fetal growth and elevated maternal serum sFLT1
fetal growth fetal stress Placental Insufficiency Pregnancy protein biomarkers spontaneous labor Adult Biomarkers Cohort Studies Female Fetal Development Gestational Age Humans Labor Obstetric Placenta Growth Factor Placental Insufficiency Pregnancy Ultrasonography Prenatal Vascular Endothelial Growth Factor Receptor-1
Associations between Maternal Iron Supplementation in Pregnancy and Changes in Offspring Size at Birth Reflect Those of Multiple Micronutrient Supplementation.
Adiposity development fetal growth Gestational diabetes Minerals Vitamins Adiposity Adult Birth Weight Body Mass Index Diabetes Gestational Dietary Supplements Female Follow-Up Studies Humans Infant Newborn Iron Dietary Male Maternal Nutritional Physiological Phenomena Micronutrients Pregnancy Prospective Studies Skinfold Thickness
Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age.
Conditions such as small for gestational age (SGA), which is defined as birthweight less than 10th percentile for gestational age can predispose to neurodevelopmental abnormalities compared to babies with normal birthweight....
Advancing human health in the decade ahead: pregnancy as a key window for discovery
Yoel Sadovsky, Sam Mesiano, Graham J Burton, Michelle Lampl, Jeffrey C Murray, Rachel M Freathy, Anita Mahadevan-Jansen, Ashley Moffett, Nathan D Price, Paul H Wise, Derek E Wildman, Ralph Snyderman, Nigel Paneth, John Anthony Capra, Marcelo A Nobrega, Yaacov Barak, Louis J Muglia, Burroughs Wellcome Fund Pregnancy Think Tank Working Group
Sep 09, 2020
Recent revolutionary advances at the intersection of medicine, omics, data sciences, computing, epidemiology, and related technologies inspire us to ponder their impact on health. Their potential impact is particularly germane...
adverse outcomes Artificial Intelligence birthweight Computational Biology developmental origins of adult disease Disparities Drug Discovery evolutionary biology fetal growth fetal growth restriction Genomics Gestational diabetes mellitus Immune Tolerance Maternal Health Metabolomics multiomics Parturition Physiology population health Precision Medicine Preeclampsia Pregnancy Preterm birth Stillbirth Economics Female Fetal Development Health Promotion Humans Perinatal Care Pregnancy Pregnancy Complications Pregnancy Outcome Psychology
Deletion of the Imprinted Phlda2 Gene Increases Placental Passive Permeability in the Mouse.
Emily Angiolini, Ionel Sandovici, Philip M Coan, Graham J Burton, Colin P Sibley, Abigail L Fowden, Miguel Constância
Apr 29, 2021
Multiple Micronutrient Supplementation during Pregnancy and Increased Birth Weight and Skinfold Thicknesses in the Offspring
Multiple micronutrient supplementation (MMS) in pregnancy has previously been associated with positive effects on fetal growth, but its value in high-income countries remains controversial. In this study, we investigated effects...
The effect of customization and use of a fetal growth standard on the association between birthweight percentile and adverse perinatal outcome.
BACKGROUND: It has been proposed that correction of offspring weight percentiles (customization) might improve the prediction of adverse pregnancy outcome; however, the approach is not accepted universally. A complication in the...
adverse perinatal outcome birthweight customization fetal growth Small for gestational age acidosis Adult Apgar Score Birth Weight Cohort Studies EXTRACTION Obstetrical Female Fetal Development Fetal Growth Retardation Growth Charts Humans Infant Newborn Infant Small for Gestational Age Intensive Care Units Neonatal Logistic Models obesity Perinatal Mortality pre-eclampsia Pregnancy Pregnancy Complications premature birth Prospective Studies Smoking United Kingdom
The Role of Placental Hormones in Mediating Maternal Adaptations to Support Pregnancy and Lactation.
During pregnancy, the mother must adapt her body systems to support nutrient and oxygen supply for growth of the baby in utero and during the subsequent lactation. These include changes in the cardiovascular, pulmonary, immune...
Associations between Maternal Iron Supplementation in Pregnancy and Changes in Offspring Size at Birth Reflect Those of Multiple Micronutrient Supplementation.
It was previously observed that in a population of a high-income country, dietary multiple micronutrient supplementation in pregnancy was associated with an increased risk of gestational diabetes (GDM) and increased offspring...
Published by: Nutrients
Beyond Maternal Tolerance
Delphine M Depierreux, Jens Kieckbusch, Norman Shreeve, Delia A Hawkes, Bryan Marsh, Robert Blelloch, Andrew Sharkey, Francesco Colucci
May 24, 2022
Reproductive immunology has moved on from the classical Medawar question of 60 years ago "why doesn't the mother reject the fetus?". Looking beyond fetal-maternal tolerance, modern reproductive immunology focuses on how the...
Birth weight to placenta weight ratio and its relationship to ultrasonic measurements, maternal and neonatal morbidity
N Salavati, SJ Gordijn, U Sovio, R Zill-E-Huma, A Gebril, DS Charnock-Jones, SA Scherjon, Gcs Smith
Mar 09, 2018
INTRODUCTION: Birth weight to placenta weight (BWPW)-ratio is an indicator of the ability of the placenta to maintain adequate nutrient supply to the fetus. We sought to investigate the relationship between BWPW-ratio with fetal...
A Western-style obesogenic diet alters maternal metabolic physiology with consequences for fetal nutrient acquisition in mice
B Musial, OR Vaughan, DS Fernandez-Twinn, P Voshol, SE Ozanne, AL Fowden, AN Sferruzzi-Perri
May 23, 2017
Developmental Ultrasound Characteristics in Guinea Pigs
Alejandro A Candia, Tamara Jiménez, Álvaro Navarrete, Felipe Beñaldo, Pablo Silva, Claudio García-Herrera, Amanda N Sferruzzi-Perri, Bernardo J Krause, Alejandro González-Candia, Emilio A Herrera
Mar 30, 2023
Background
Biometrical and blood flow examinations are fundamental for assessing fetoplacental development during pregnancy. Guinea pigs have been proposed as a good model to study fetal development and related...
Published by: Veterinary sciences
Pregnancy Serum DLK1 Concentrations Are Associated With Indices of Insulin Resistance and Secretion.
Clive J Petry, Keith A Burling, Peter Barker, Ieuan A Hughes, Ken K Ong, David B Dunger
Feb 24, 2021
FA1 PREF1 fetal growth imprinted Pregnancy Adult Birth Weight Calcium-Binding Proteins Diabetes Gestational Female Fetal Development Glucose Tolerance Test Health Status Indicators Humans Hypertension Pregnancy-Induced Infant Newborn Insulin Insulin Resistance Longitudinal Studies Male Membrane Proteins Pregnancy United Kingdom