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G4Dfsc is a de novo designed, single-chain four-helix bundle protein created to mimic the properties of diiron carboxylate enzymes. The active sites of these proteins are comprised of two iron atoms ligated by two histidine and...

model proteins metalloenzymes de novo proteins flavo-diiron enzymes binding affinity Biochemistry Biochemistry, Biophysics, and Structural Biology Life Sciences Molecular Biology