Increased Frequency of CD4+ Follicular Helper T and CD8+ Follicular T Cells in Human Lymph Node Biopsies during the Earliest Stages of Rheumatoid Arthritis.
Dornatien Chuo Anang,
Tamara H Ramwadhdoebe,
Janine S Hähnlein,
Bo van Kuijk,
Noortje Smits,
Krijn P van Lienden,
Mario Maas,
Daniëlle M Gerlag,
Paul P Tak,
Niek de Vries,
Lisa GM van Baarsen
Mar 28, 2022
Follicular T helper cells (Tfh cells) provide key B-cell help and are essential in germinal center formation and (auto) antibody generation. To gain more insight into their role during the earliest phase of rheumatoid arthritis...