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Lamin A/C modulates spatial organization and function of the Hsp70 gene locus via nuclear myosin I.
The structure-function relationship of the nucleus is tightly regulated, especially during heat shock. Typically, heat shock activates molecular chaperones that prevent protein misfolding and preserve genome integrity. However...
Stress-induced recombination and the mechanism of evolvability
The concept of evolvability is controversial. To some, it is simply a measure of the standing genetic variation in a population and can be captured by the narrow-sense heritability (h(2)). To others, evolvability refers to the...
SWATH-MS dataset of heat-shock treated Drosophila melanogaster embryos.
Bertrand Fabre, Dagmara Korona, Daniel JH Nightingale, Steven Russell, Kathryn S Lilley
Nov 20, 2017
Data independent acquisition (DIA) has emerged as a promising mass spectrometry based approach, combining the advantages of shotgun and targeted proteomics. Here we applied a DIA approach (termed SWATH) to monitor the dynamics...
Stress-induced recombination and the mechanism of evolvability
The concept of evolvability is controversial. To some, it is simply a measure of the standing genetic variation in a population and can be captured by the narrow-sense heritability (h(2)). To others, evolvability refers to the...