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Design, development, and validation of a strand-specific RT-qPCR assay for GI and GII human Noroviruses.
Katja Marie Kjara König, Aminu S Jahun, Komal Nayak, Lydia N Drumright, Matthias Zibauer, Ian Goodfellow, Myra Hosmillo
Jan 06, 2022
Human noroviruses (HuNoV) are the major cause of viral gastroenteritis worldwide. Similar to other positive-sense single-stranded RNA viruses, norovirus RNA replication requires the formation of a negative strand RNA...
Butyrate Produced by Commensal Bacteria Down-Regulates Indolamine 2,3-Dioxygenase 1 (IDO-1) Expression via a Dual Mechanism in Human Intestinal Epithelial Cells.
Camille Martin-Gallausiaux, Pierre Larraufie, Anne Jarry, Fabienne Béguet-Crespel, Ludovica Marinelli, Florence Ledue, Frank Reimann, Hervé M Blottière, Nicolas Lapaque
Dec 20, 2018
Commensal bacteria are crucial for the development and maintenance of a healthy immune system therefore contributing to the global well-being of their host. A wide variety of metabolites produced by commensal bacteria are...
IDO-1 butyrate Gut microbiota immune gene regulation intestinal epithelial cells Bacteria Butyric Acid Caco-2 Cells Down-Regulation Epithelial Cells Female Gastrointestinal Microbiome Gene Expression Regulation Developmental Humans Indoleamine-Pyrrole 2 3 -Dioxygenase Interferon-gamma Intestinal Mucosa Male Middle Aged Receptors G-Protein-Coupled Transcription Factors
Development of caecaloids to study host-pathogen interactions
María A Duque-Correa, Fernanda Schreiber, Faye H Rodgers, David Goulding, Sally Forrest, Ruby White, Amy Buck, Richard K Grencis, Matthew Berriman
Sep 15, 2020
The caecum, an intestinal appendage in the junction of the small and large intestines, displays a unique epithelium that serves as an exclusive niche for a range of pathogens including whipworms (Trichuris spp.). While protocols...
Design, development, and validation of a strand-specific RT-qPCR assay for GI and GII human Noroviruses.
Katja Marie Kjara König, Aminu Jahun, Komal Nayak, Lydia N Drumright, Matthias Zibauer, Ian Goodfellow, Myra Hosmillo
Nov 03, 2021
Human noroviruses (HuNoV) are the major cause of viral gastroenteritis worldwide. Similar to other positive-sense single-stranded RNA viruses, norovirus RNA replication requires the formation of a negative strand RNA...