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DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development.
Judith Kraiczy, Komal M Nayak, Kate J Howell, Alexander Ross, Jessica Forbester, Camilla Salvestrini, Roxana Mustata, Sally Perkins, Amanda Andersson-Rolf, Esther Leenen, Anke Liebert, Ludovic Vallier, Philip C Rosenstiel, Oliver Stegle, Gordon Dougan, Robert Heuschkel, Bon-Kyoung Koo, Matthias Zilbauer
May 31, 2018
intestinal cell lines intestinal development Intestinal Epithelium intestinal gene regulation intestinal stem cell Cell Differentiation Cells Cultured Clustered Regularly Interspaced Short Palindromic Repeats DNA Methylation Epigenesis Genetic Epithelial Cells Humans Intestinal Mucosa Organoids Transcriptome