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Cutting edge: Langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo
The targeted delivery of Ags to dendritic cell (DCs) in vivo greatly improves the efficiency of Ag presentation to T cells and allows an analysis of receptor function. To evaluate the function of Langerin/CD207, a receptor...
Published by: Rockefeller University
Specialized role of migratory dendritic cells in peripheral tolerance induction
Harnessing DCs for immunotherapies in vivo requires the elucidation of the physiological role of distinct DC populations. Migratory DCs traffic from peripheral tissues to draining lymph nodes charged with tissue self antigens....
CD8 antigen langerin cell migration dendritic cell molecularly targeted therapy Langerhans Cells regulatory T lymphocyte
Published by: Rockefeller University
Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells
Skin-derived dendritic cells (DCs) are potent antigen-presenting cells with critical roles in both adaptive immunity and tolerance to self. Skin DCs carry antigens and constitutively migrate to the skin-draining lymph nodes...
CD11b Antigen langerin dendritic cell chemokine receptors Flow Cytometry Microarray Analysis T lymphocyte
Published by: Rockefeller University