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Functional proteomic atlas of HIV infection in primary human CD4+ T cells.
Adi Naamati, James C Williamson, Edward JD Greenwood, Sara Marelli, Paul J Lehner, Nicholas J Matheson
Mar 28, 2019
Viruses manipulate host cells to enhance their replication, and the identification of cellular factors targeted by viruses has led to key insights into both viral pathogenesis and cell biology. In this study, we develop an HIV...
HIV human immunology infectious disease Inflammation magnetic cell selection microbiology primary human CD4+ T cell Proteomics Virus CD4-Positive T-Lymphocytes Cell Separation Cluster Analysis DNA-Binding Proteins Fragile X Mental Retardation Protein Gene Expression Regulation Green Fluorescent Proteins HIV Infections HIV-1 Humans Hydrogen-Ion Concentration Lentivirus Lymphocyte Activation Magnetics Methyltransferases Protein Binding Protein Tyrosine Phosphatase Non-Receptor Type 22 Proteome Proteomics Streptavidin Virus Replication vif Gene Products Human Immunodeficiency Virus