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Results: 1
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Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers.
Ryan P Kreiser
,
Aidan K Wright
,
Natalie R Block
,
Jared E Hollows
,
Lam T Nguyen
,
Kathleen LeForte
,
Benedetta Mannini
,
Michele Vendruscolo
,
Ryan Limbocker
Nov 19, 2020
The aberrant aggregation of proteins is implicated in the onset and pathogenesis of a wide range of neurodegenerative disorders, including Alzheimer's and Parkinson's diseases. Mounting evidence indicates that misfolded protein...
Alzheimer’s disease
Parkinson’s disease
countermeasures
Kinetics
membrane protection
misfolded protein oligomers
Protein homeostasis
structure–toxicity relationships
Animals
Humans
protein aggregation
Pathological
Protein Multimerization
Proteostasis Deficiencies
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