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Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin
To determine whether strong CD4+ T cell immunity could be induced to a nonmutated self protein that is important for tumorigenesis, we selectively targeted the xenogencic form of survivin, a survival protein overexpressed in...
antigen specificity CD4+ T lymphocyte cytokine production memory T lymphocyte dendritic cell T cell depletion
Published by: Rockefeller University