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Gluconeogenic precursor availability regulates flux through the glyoxylate shunt in Pseudomonas aeruginosa.
The glyoxylate shunt bypasses the oxidative decarboxylation steps of the tricarboxylic acid (TCA) cycle, thereby conserving carbon skeletons for gluconeogenesis and biomass production. In Escherichia coli, carbon flux is...
Pseudomonas aeruginosa acetyl coenzyme A (acetyl-CoA) Allosteric Regulation bacterial metabolism bacterial pathogenesis bacterial virulence enzyme regulation enzyme structure Gluconeogenesis glyoxylate shunt Isocitrate Dehydrogenase isocitrate lyase metabolic adaptation metabolic regulation post-translational modification (PTM) tricarboxylic acid cycle (TCA cycle) (Krebs cycle) Acetyl Coenzyme A Citric Acid Cycle Crystallography X-Ray Decarboxylation Escherichia coli Gluconeogenesis Glyoxylates Isocitrate Dehydrogenase Isocitrate Lyase Kinetics Oxaloacetic Acid Phosphorylation Pseudomonas aeruginosa
Translational regulation by Hfq-Crc assemblies emerges from polymorphic ribonucleoprotein folding.
Insulin signaling requires glucose to promote lipid anabolism in adipocytes.
James R Krycer, Lake-Ee Quek, Deanne Francis, Armella Zadoorian, Fiona C Weiss, Kristen C Cooke, Marin E Nelson, Alexis Diaz-Vegas, Sean J Humphrey, Richard Scalzo, Akiyoshi Hirayama, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Kevin Huynh, Corey Giles, Bianca Varney, Shilpa R Nagarajan, Andrew J Hoy, Tomoyoshi Soga, Peter J Meikle, Gregory J Cooney, Daniel J Fazakerley, David E James
Aug 27, 2020
Adipose tissue is essential for metabolic homeostasis, balancing lipid storage and mobilization based on nutritional status. This is coordinated by insulin, which triggers kinase signaling cascades to modulate numerous metabolic...
Protein- A nd Calcium-Mediated GLP-1 Secretion
Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced in the intestine which is secreted in response to nutrient exposure. GLP-1 potentiates glucose-dependent insulin secretion from the pancreatic beta cells and...
GLP-1 Calcium extracellular calcium-sensing receptor metabolic regulation protein Type 2 diabetes /dk/atira/pure/subjectarea/asjc/1100/1106 name=Food Science /dk/atira/pure/subjectarea/asjc/2700/2701 name=Medicine (miscellaneous) /dk/atira/pure/subjectarea/asjc/2900/2916 name=Nutrition and Dietetics /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Protein- A nd Calcium-Mediated GLP-1 Secretion
Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced in the intestine which is secreted in response to nutrient exposure. GLP-1 potentiates glucose-dependent insulin secretion from the pancreatic beta cells and...
GLP-1 Calcium extracellular calcium-sensing receptor metabolic regulation protein Type 2 diabetes /dk/atira/pure/subjectarea/asjc/1100/1106 name=Food Science /dk/atira/pure/subjectarea/asjc/2700/2701 name=Medicine (miscellaneous) /dk/atira/pure/subjectarea/asjc/2900/2916 name=Nutrition and Dietetics /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Architectural principles for Hfq/Crc-mediated regulation of gene expression.
Xue Yuan Pei, Tom Dendooven, Elisabeth Sonnleitner, Shaoxia Chen, Udo Bläsi, Ben F Luisi
May 09, 2019
Pseudomonas aeruginosa metabolic regulation molecular biophysics riboregulation structural biology Bacterial Proteins Catabolite Repression Cryoelectron Microscopy Gene Expression Regulation Bacterial Host Factor 1 Protein Multiprotein Complexes Peptide Chain Initiation Translational Promoter Regions Genetic Protein Conformation Pseudomonas aeruginosa RNA Bacterial RNA Messenger Repressor Proteins