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A NuRD Complex from Xenopus laevis Eggs Is Essential for DNA Replication during Early Embryogenesis.
Christo P Christov, Kevin S Dingwell, Mark Skehel, Helen S Wilkes, Julian E Sale, James C Smith, Torsten Krude
Apr 20, 2018
DNA replication in the embryo of Xenopus laevis changes dramatically at the mid-blastula transition (MBT), with Y RNA-independent random initiation switching to Y RNA-dependent initiation at specific origins. Here, we identify...
DNA Replication NuRD Xenopus laevis Y RNA chromatin remodeling development Histone deacetylase initiation mid-blastula transition Non-coding RNA Animals Blastula Cell Extracts DNA Replication Embryonic Development HeLa Cells Humans Mi-2 Nucleosome Remodeling and Deacetylase Complex Ovum RNA Xenopus laevis