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Cover Image for Single-molecule analysis of endogenous β-actin mRNA trafficking reveals a mechanism for compartmentalized mRNA localization in axons. View Article
Single-molecule analysis of endogenous β-actin mRNA trafficking reveals a mechanism for compartmentalized mRNA localization in axons.
Benita Turner-Bridger, Maximillian Jakobs, Leila Muresan, Hovy Ho-Wai Wong, Kristian Franze, William A Harris, Christine E Holt
Nov 22, 2018
During embryonic nervous system assembly, mRNA localization is precisely regulated in growing axons, affording subcellular autonomy by allowing controlled protein expression in space and time. Different sets of mRNAs exhibit...
RNA localization axon molecular beacon Single molecule β-actin Actins Animals Biological Transport Active Growth Cones Models Biological Molecular Imaging Neurogenesis RNA Messenger Xenopus Proteins Xenopus laevis
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