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multi-armed bandit Gittins index response adaptive procedures normally distributed endpoint sequential sampling patient allocation

The Gittins index provides a well established, computationally attractive, optimal solution to a class of resource allocation problems known collectively as the multi-arm bandit problem. Its development was originally motivated...

Bayesian adaptive designs Clinical Trials Gittins index multi-armed bandit Sequential allocation Algorithms Bayes Theorem Biometry Computer Simulation Humans Inflammatory Breast Neoplasms Models Statistical Randomized Controlled Trials as Topic

Multi-armed bandit problems (MABPs) are a special type of optimal control problem well suited to model resource allocation under uncertainty in a wide variety of contexts. Since the first publication of the optimal solution of...

Gittins index multi-armed bandit Whittle index patient allocation response adaptive procedures

adaptive designs CARA randomization ethics multi-armed bandit Sequential allocation Clinical Trials as Topic Humans Models Statistical Random Allocation therapeutics Treatment Failure