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Results: 11
Clinically Interpretable Radiomics-Based Prediction of Histopathologic Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma.
Leonardo Rundo, Lucian Beer, Lorena Escudero Sanchez, Mireia Crispin-Ortuzar, Marika Reinius, Cathal McCague, Hilal Sahin, Vlad Bura, Roxana Pintican, Marta Zerunian, Stephan Ursprung, Iris Allajbeu, Helen Addley, Paula Martin-Gonzalez, Thomas Buddenkotte, Naveena Singh, Anju Sahdev, Ionut-Gabriel Funingana, Mercedes Jimenez-Linan, Florian Markowetz, James D Brenton, Evis Sala, Ramona Woitek
Jun 30, 2022
BACKGROUND: Pathological response to neoadjuvant treatment for patients with high-grade serous ovarian carcinoma (HGSOC) is assessed using the chemotherapy response score (CRS) for omental tumor deposits. The main limitation of...
The NeST (neoadjuvant systemic therapy in breast cancer) study - Protocol for a prospective multi-centre cohort study to assess the current utilization and short-term outcomes of neoadjuvant systemic therapies in breast cancer.
GW Irwin, F Bannon, CE Coles, E Copson, RI Cutress, RV Dave, M Grayson, C Holcombe, S Irshad, C O'Brien, RL O'Connell, C Palmieri, AM Shaaban, N Sharma, J Singh, I Whitehead, S Potter, SA McIntosh
Feb 04, 2020
INTRODUCTION: Neoadjuvant systemic therapy (NST) has several potential advantages in the treatment of breast cancer. However, there is currently considerable variation in NST use across the UK. The NeST study is a national...
Prognostic Relevance of Neutrophil to Lymphocyte Ratio (NLR) in Luminal Breast Cancer
Antonino Grassadonia, Vincenzo Graziano, Laura Iezzi, Patrizia Vici, Maddalena Barba, Laura Pizzuti, Giuseppe Cicero, Eriseld Krasniqi, Marco Mazzotta, Daniele Marinelli, Antonella Amodio, Clara Natoli, Nicola Tinari
Sep 08, 2021
The neutrophil to lymphocyte ratio (NLR) is a promising predictive and prognostic factor in breast cancer. We investigated its ability to predict disease-free survival (DFS) and overall survival (OS) in patients with luminal A-...
Luminal breast cancer neoadjuvant chemotherapy neutrophil to lymphocyte ratio (NLR) predictive/prognostic biomarkers Adult Aged Breast Neoplasms Disease-Free Survival Female Humans Ki-67 Antigen Lymphocytes Middle Aged Multivariate Analysis Neoadjuvant Therapy Neutrophils Prognosis Retrospective Studies Treatment Outcome
Staging Breast Cancer with MRI, the T. A Key Role in the Neoadjuvant Setting.
Camilla Panico, Francesca Ferrara, Ramona Woitek, Anna D'Angelo, Valerio Di Paola, Enida Bufi, Marco Conti, Simone Palma, Stefano Lo Cicero, Giovanni Cimino, Paolo Belli, Riccardo Manfredi
Dec 08, 2022
The 2018 assisi think tank meeting on breast cancer
Meritxell Arenas, Ugur Selek, Orit Kaidar-Person, Elisabetta Perrucci, Angel Montero Luis, Liesbeth Boersma, Charlotte Coles, Birgitte Offersen, Icro Meattini, Yasemin Bölükbaşı, Maria Cristina Leonardi, Raphael Pfeffer, Bruno Cutuli, Cristiana Vidali, Pierfrancesco Franco, Vassilis Kouloulias, Valeria Masiello, Sofia Rivera, Céline Bourgier, Antonella Ciabattoni, Valentina Lancellotta, Lurdes Trigo, Vincenzo Valentini, Philip Poortmans, Cynthia Aristei
Jun 24, 2020
We report on the second Assisi Think Tank Meeting (ATTM) on breast cancer which was held under the auspices of the European Society for RadioTherapy & Oncology (ESTRO). In discussing in-depth current evidence and practice it was...
Breast Cancer Breast reconstruction De-escalating therapy Ductal carcinoma in situ Hypofractionation neoadjuvant chemotherapy Partial breast irradiation Post-mastectomy radiation therapy Radiation therapy Breast Neoplasms Carcinoma Intraductal Noninfiltrating Humans Mastectomy Mastectomy Segmental Radiotherapy Adjuvant
Pre-operative stromal stiffness measured by shear wave elastography is independently associated with breast cancer-specific survival.
Andy Evans, Yee Ting Sim, Celine Pourreyron, Alastair Thompson, Lee Jordan, Dawn Fleming, Colin Purdie, Jane Macaskill, Sarah Vinnicombe, Paul Pharoah
Oct 10, 2018
INTRODUCTION: With the increased use of neoadjuvant therapy for breast cancer, there is a need for pre-operative prediction of prognosis. We aimed to assess the prognostic value of tumour stiffness measured by ultrasound shear...
Breast Cancer neoadjuvant chemotherapy Prognosis Shear wave elastography ULTRASOUND Adult Aged Aged 80 and over Biomarkers Breast Neoplasms Elasticity Elasticity Imaging Techniques Female Humans Kaplan-Meier Estimate Middle Aged Neoplasm Grading Neoplasm Staging Preoperative Period Prognosis Tumor Microenvironment
Lymphocyte density determined by computational pathology validated as a predictor of response to neoadjuvant chemotherapy in breast cancer
HR Ali, A Dariush, J Thomas, E Provenzano, J Dunn, L Hiller, A-L Vallier, J Abraham, T Piper, JMS Bartlett, DA Cameron, L Hayward, JD Brenton, PDP Pharoah, M Irwin, NA Walton, HM Earl, C Caldas
Jul 20, 2017
Background: Patients and methods: Results: Conclusions:
Axillary Surgery Following Neoadjuvant Chemotherapy - Multidisciplinary Guidance From the Association of Breast Surgery, Faculty of Clinical Oncology of the Royal College of Radiologists, UK Breast Cancer Group, National Coordinating Committee for Breast Pathology and British Society of Breast Radiology.
AIMS: These multidisciplinary guidelines aim to provide clinically helpful, evidence-based recommendations on the surgical management of the axilla in patients who have received neo-adjuvant chemotherapy for early breast cancer....
Prognostic Relevance of Neutrophil to Lymphocyte Ratio (NLR) in Luminal Breast Cancer
Antonino Grassadonia, Vincenzo Graziano, Laura Iezzi, Patrizia Vici, Maddalena Barba, Laura Pizzuti, Giuseppe Cicero, Eriseld Krasniqi, Marco Mazzotta, Daniele Marinelli, Antonella Amodio, Clara Natoli, Nicola Tinari
Jul 07, 2021
The neutrophil to lymphocyte ratio (NLR) is a promising predictive and prognostic factor in breast cancer. We investigated its ability to predict disease-free survival (DFS) and overall survival (OS) in patients with luminal A-...
Staging Breast Cancer with MRI, the T. A Key Role in the Neoadjuvant Setting.
Camilla Panico, Francesca Ferrara, Ramona Woitek, Anna D'Angelo, Valerio Di Paola, Enida Bufi, Marco Conti, Simone Palma, Stefano Lo Cicero, Giovanni Cimino, Paolo Belli, Riccardo Manfredi
Jan 10, 2023
Breast cancer (BC) is the most common cancer among women worldwide. Neoadjuvant chemotherapy (NACT) indications have expanded from inoperable locally advanced to early-stage breast cancer. Achieving a pathological complete...
Disease-free and overall survival at 3.5 years for neoadjuvant bevacizumab added to docetaxel followed by fluorouracil, epirubicin and cyclophosphamide, for women with HER2 negative early breast cancer
HM Earl, L Hiller, J Dunn, C Blenkinsop, L Grybowicz, A-L Vallier, I Gounaris, J Abraham, L Hughes-Davies, K McAdam, S Chan, R Ahmad, T Hickish, D Rea, C Caldas, JMS Bartlett, DA Cameron, E Provenzano, J Thomas, RL Hayward, ARTemis Investigators Group
Jul 03, 2017