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Nonstructural proteins nsp2TF and nsp2N of porcine reproductive and respiratory syndrome virus (PRRSV) play important roles in suppressing host innate immune responses.
Y Li, P Shang, D Shyu, C Carrillo, P Naraghi-Arani, Crystal J Jaing, GJ Renukaradhya, AE Firth, EJ Snijder, Y Fang
Mar 02, 2018
Recently, we identified a unique -2/-1 ribosomal frameshift mechanism in PRRSV, which yields two truncated forms of nonstructural protein (nsp) 2 variants, nsp2TF and nsp2N. Here, in vitro expression of individual PRRSV nsp2TF...
Innate immune response PRRSV Ribosomal frameshift nsp2N nsp2TF Animals Cell Line Chlorocebus aethiops Gene Expression Regulation Immunity Innate Porcine Reproductive and Respiratory Syndrome Porcine respiratory and reproductive syndrome virus RNA Messenger Swine Up-Regulation Viral Nonstructural Proteins