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Induced Arp2/3 Complex Depletion Increases FMNL2/3 Formin Expression and Filopodia Formation.
Vanessa Dimchev, Ines Lahmann, Stefan A Koestler, Frieda Kage, Georgi Dimchev, Anika Steffen, Theresia EB Stradal, Franz Vauti, Hans-Henning Arnold, Klemens Rottner
Mar 18, 2021
The Arp2/3 complex generates branched actin filament networks operating in cell edge protrusion and vesicle trafficking. Here we employ a conditional knockout mouse model permitting tissue- or cell-type specific deletion of the...