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Cause of Cambrian Explosion - Terrestrial or Cosmic?
Edward J Steele, Shirwan Al-Mufti, Kenneth A Augustyn, Rohana Chandrajith, John P Coghlan, SG Coulson, Sudipto Ghosh, Mark Gillman, Reginald M Gorczynski, Brig Klyce, Godfrey Louis, Kithsiri Mahanama, Keith R Oliver, Julio Padron, Jiangwen Qu, John A Schuster, WE Smith, Duane P Snyder, Julian A Steele, Brent J Stewart, Robert Temple, Gensuke Tokoro, Christopher A Tout, Alexander Unzicker, Milton Wainwright, Jamie Wallis, Daryl H Wallis, Max K Wallis, John Wetherall, DT Wickramasinghe, JT Wickramasinghe, N Chandra Wickramasinghe, Yongsheng Liu
Jun 12, 2018
We review the salient evidence consistent with or predicted by the Hoyle-Wickramasinghe (H-W) thesis of Cometary (Cosmic) Biology. Much of this physical and biological evidence is multifactorial. One particular focus are the...
Rolling circle RNA synthesis catalyzed by RNA.
RNA-catalyzed RNA replication is widely considered a key step in the emergence of life's first genetic system. However, RNA replication can be impeded by the extraordinary stability of duplex RNA products, which must be...
Marine phosphate availability and the chemical origins of life on Earth.
Prebiotic systems chemistry suggests that high phosphate concentrations were necessary to synthesise molecular building blocks and sustain primitive cellular systems. However, current understanding of mineral solubility predicts...
On the differing growth mechanisms of black-smoker and Lost City-type hydrothermal vents.
Black smokers and Lost City-type springs are varieties of hydrothermal vents on the ocean floors that emit hot, acidic water and cool, alkaline water, respectively. While both produce precipitation structures as the issuing...
Cysteine and iron accelerate the formation of ribose-5-phosphate, providing insights into the evolutionary origins of the metabolic network structure.
Gabriel Piedrafita, Sreejith J Varma, Cecilia Castro, Christoph B Messner, Lukasz Szyrwiel, Julian L Griffin, Markus Ralser
Jan 05, 2022
The structure of the metabolic network is highly conserved, but we know little about its evolutionary origins. Key for explaining the early evolution of metabolism is solving a chicken-egg dilemma, which describes that enzymes...
Scum of the Earth
Compartmentalisation by bioenergetic membranes is a universal feature of life. The eventual compartmentalisation of prebiotic systems is therefore often argued to comprise a key step during the origin of life. Compartments may...
Frontiers in Prebiotic Chemistry and Early Earth Environments.
Ulrich F Müller, Jamie Elsila, Dustin Trail, Saurja DasGupta, Claudia-Corina Giese, Craig R Walton, Zachary R Cohen, Tomislav Stolar, Ramanarayanan Krishnamurthy, Timothy W Lyons, Karyn L Rogers, Loren Dean Williams
Aug 07, 2022
The Prebiotic Chemistry and Early Earth Environments (PCE3) Consortium is a community of researchers seeking to understand the origins of life on Earth and in the universe. PCE3 is one of five Research Coordination Networks...
Origin of Life's Building Blocks in Carbon- and Nitrogen-Rich Surface Hydrothermal Vents.
There are two dominant and contrasting classes of origin of life scenarios: those predicting that life emerged in submarine hydrothermal systems, where chemical disequilibrium can provide an energy source for nascent life; and...
Mimicking the surface and prebiotic chemistry of early Earth using flow chemistry.
When considering life's aetiology, the first questions that must be addressed are "how?" and "where?" were ostensibly complex molecules, considered necessary for life's beginning, constructed from simpler, more abundant...
Scum of the Earth
Compartmentalisation by bioenergetic membranes is a universal feature of life. The eventual compartmentalisation of prebiotic systems is therefore often argued to comprise a key step during the origin of life. Compartments may...