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Differentiation of mild cognitive impairment using an entorhinal cortex-based test of virtual reality navigation.
David Howett, Andrea Castegnaro, Katarzyna Krzywicka, Johanna Hagman, Deepti Marchment, Richard Henson, Miguel Rio, John A King, Neil Burgess, Dennis Chan
Jun 17, 2019
The entorhinal cortex is one of the first regions to exhibit neurodegeneration in Alzheimer's disease, and as such identification of entorhinal cortex dysfunction may aid detection of the disease in its earliest stages....
Alzheimer’s disease Entorhinal Cortex mild cognitive impairment path integration virtual reality Aged Aged 80 and over Alzheimer Disease Amyloid beta-Peptides Biomarkers Cognitive Dysfunction Diagnosis Differential Early Diagnosis Entorhinal Cortex Female Humans Magnetic Resonance Imaging Male Middle Aged Neuropsychological Tests Sensitivity and Specificity virtual reality