Determination of IgG1 and IgG3 SARS-CoV-2 Spike Protein and Nucleocapsid Binding-Who Is Binding Who and Why?
Jason K Iles,
Raminta Zmuidinaite,
Christoph Sadee,
Anna Gardiner,
Jonathan Lacey,
Stephen Harding,
Gregg Wallis,
Roshani Patel,
Debra Roblett,
Jonathan Heeney,
Helen Baxendale,
Ray Kruse Iles
May 30, 2022
The involvement of immunoglobulin (Ig) G3 in the humoral immune response to SARS-CoV-2 infection has been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS) in COVID-19. The exact molecular mechanism is...