Search
Results: 59
Are female children more vulnerable to the long-term effects of maternal depression during pregnancy?
Catherine Quarini, Rebecca M Pearson, Alan Stein, Paul G Ramchandani, Glyn Lewis, Jonathan Evans
Jan 08, 2019
BACKGROUND: Female fetuses are more vulnerable to high levels of maternal glucocorticoids. We examined whether exposure to prenatal maternal depression, a condition associated with high glucocorticoids, carries greater risk for...
Suckling a protein-restricted rat dam leads to diminished albuminuria in her male offspring in adult life
BACKGROUND: Previous studies have shown that in male rats, exposure to maternal protein restriction either in utero or whilst suckling can have profound effects on both longevity and kidney telomere lengths. This study monitored...
Prenatal androgen exposure and children's gender-typed behavior and toy and playmate preferences.
Debra Spencer, Vickie Pasterski, Sharon AS Neufeld, Vivette Glover, Thomas G O'Connor, Peter C Hindmarsh, Ieuan A Hughes, Carlo L Acerini, Melissa Hines
Nov 17, 2020
amniotic fluid testosterone androgen congenital adrenal hyperplasia Gender-typed play behavior Playmate preferences prenatal testosterone exposure Sex differences Toy preferences Adrenal Hyperplasia Congenital Amniotic Fluid Androgens Case-Control Studies Child Child Preschool Choice Behavior Female Friends Gender Identity Humans Interpersonal Relations Male Play and Playthings Pregnancy prenatal exposure delayed effects Sex Characteristics Testosterone
Maternal Metformin Intervention during Obese Glucose-Intolerant Pregnancy Affects Adiposity in Young Adult Mouse Offspring in a Sex-Specific Manner.
Josca M Schoonejans, Heather L Blackmore, Thomas J Ashmore, Catherine E Aiken, Denise S Fernandez-Twinn, Susan E Ozanne
Jul 27, 2021
BACKGROUND: Metformin is commonly used to treat gestational diabetes mellitus. This study investigated the effect of maternal metformin intervention during obese glucose-intolerant pregnancy on the gonadal white adipose tissue...
Maternal diet, aging and diabetes meet at a chromatin loop.
Maternal prenatal stress and placental gene expression of NR3C1 and HSD11B2
BACKGROUND: Prenatal stress is associated with altered fetal and infant development. Previous studies have suggested that these effects may be mediated in part via altered functioning of placental enzymes and receptors involved...
Anxiety Depression Placenta and ethnicity Prenatal 11-beta-Hydroxysteroid Dehydrogenase Type 2 Adult Anxiety Anxiety Disorders Depression Depressive Disorder Down-Regulation Ethnicity Female Gene Expression Gene Expression Regulation Humans Hydrocortisone Placenta Pregnancy Pregnant Women prenatal exposure delayed effects Receptors Glucocorticoid Stress Psychological
Differential effects of exposure to maternal obesity or maternal weight loss during the periconceptional period in the sheep on insulin signalling molecules in skeletal muscle of the offspring at 4 months of age.
Lisa M Nicholas, Janna L Morrison, Leewen Rattanatray, Susan E Ozanne, Dave O Kleemann, Simon K Walker, Severence M MacLaughlin, Song Zhang, Malgorzata S Martin-Gronert, Isabella C McMillen
Aug 12, 2020
Exposure to maternal obesity before and/or throughout pregnancy may increase the risk of obesity and insulin resistance in the offspring in childhood and adult life, therefore, resulting in its transmission into subsequent...
Influences of pre- and postnatal nutritional exposures on vascular/endocrine systems in animals.
Human epidemiological and animal studies have revealed the long-term effects of malnutrition during gestation and early life on the health of the offspring. The aim of the current review is to survey the different means of...
Associations Between Maternal Prenatal C-Reactive Protein and Risk Factors for Psychosis in Adolescent Offspring
Hugh Ramsay, Heljä-Marja Surcel, Lassi Björnholm, Martta Kerkelä, Golam M Khandaker, Juha Veijola
Sep 24, 2020
Prenatal infection is associated with brain structural and functional abnormalities and may increase the risk for psychosis through a direct effect on neurodevelopment. Various infections may exert their effect through a...
Intervention against hypertension in the next generation programmed by developmental hypoxia.
Kirsty L Brain, Beth J Allison, Youguo Niu, Christine M Cross, Nozomi Itani, Andrew D Kane, Emilio A Herrera, Katie L Skeffington, Kimberley J Botting, Dino A Giussani
Jan 21, 2019
Maternal diet-induced obesity programmes cardiac dysfunction in male mice independently of post-weaning diet.
Elena Loche, Heather L Blackmore, Asha A Carpenter, Jessica H Beeson, Adele Pinnock, Thomas J Ashmore, Catherine E Aiken, Juliana de Almeida-Faria, Josca M Schoonejans, Dino A Giussani, Denise S Fernandez-Twinn, Susan E Ozanne
Jun 04, 2018
Age Factors Animal Nutritional Physiological Phenomena Animals Disease Models Animal Female Gestational Weight Gain Heart Diseases Hypertension Male Maternal Nutritional Physiological Phenomena Mice Inbred C57BL Myocardial Contraction Myocytes Cardiac Nutritional Status obesity Pregnancy prenatal exposure delayed effects Ventricular Function Left Ventricular Remodeling
Poor maternal nutrition programmes a pro-atherosclerotic phenotype in ApoE-/- mice.
Heather L Blackmore, Ana V Piekarz, Denise S Fernandez-Twinn, John R Mercer, Nichola Figg, Martin Bennett, Susan E Ozanne
Aug 11, 2017
Lipid traffic analysis reveals the impact of high paternal carbohydrate intake on offsprings’ lipid metabolism
Samuel Furse, Adam Watkins, Nima Hojat, James Smith, Huw Williams, Davide Chiarugi, Albert Koulman
Jan 11, 2021
From molecules to neural morphology
Adam MH Young, Bhismadev Chakrabarti, David Roberts, Meng-Chuan Lai, John Suckling, Simon Baron-Cohen
Sep 12, 2016
autism Brain Inflammation NF-κB Amniotic Fluid Animals Antigens surface Autism spectrum disorder Autoantibodies Body Fluids Brain Brain Chemistry Chemokines Cytokines Female Glutamic Acid HLA Antigens Haplorhini Humans Immunity Maternally-Acquired Inflammation Inflammation Mediators Lipopolysaccharides Maternal-Fetal Exchange Mice Nerve Tissue Proteins Neuroglia Neuroimaging Pregnancy Pregnancy Complications Infectious prenatal exposure delayed effects Signal Transduction
The effects of pre- and postnatal depression in fathers
Paul G Ramchandani, Thomas G O'Connor, Jonathan Evans, Jon Heron, Lynne Murray, Alan Stein
Jan 08, 2019
BACKGROUND: Depression in fathers in the postnatal period is associated with an increased risk of behavioural problems in their offspring, particularly for boys. The aim of this study was to examine for differential effects of...
Transgenerational transmission of hedonic behaviors and metabolic phenotypes induced by maternal overnutrition.
Gitalee Sarker, Rebecca Berrens, Judith von Arx, Pawel Pelczar, Wolf Reik, Christian Wolfrum, Daria Peleg-Raibstein
Jun 17, 2019
Maternal overnutrition has been associated with increased susceptibility to develop obesity and neurological disorders later in life. Most epidemiological as well as experimental studies have focused on the metabolic...
No moderating effect of 5-HTTLPR on associations between antenatal anxiety and infant behavior.
Elizabeth C Braithwaite, Paul G Ramchandani, Thomas G O'Connor, Marinus H van IJzendoorn, Marian J Bakermans-Kranenburg, Vivette Glover, Elena Netsi, Jonathan Evans, Michael J Meaney, Susannah E Murphy
Dec 08, 2020
OBJECTIVE: Maternal antenatal anxiety is associated with an increased risk of behavioral disturbances in offspring. Recent work has suggested that the effect of maternal antenatal anxiety on infant temperament at 6 months is...
A post-weaning obesogenic diet exacerbates the detrimental effects of maternal obesity on offspring insulin signaling in adipose tissue
Catch-up growth following intra-uterine growth-restriction programmes an insulin-resistant phenotype in adipose tissue.
BACKGROUND: It is now widely accepted that the early-life nutritional environment is important in determining susceptibility to metabolic diseases. In particular, intra-uterine growth restriction followed by accelerated...
Adipocytes Adipose Tissue Animals Blotting Western Body Weight Diabetes mellitus Type 2 Female Fetal Development Fetal Growth Retardation Gene Expression Insulin Insulin Resistance Male Metabolic Syndrome obesity Phenotype Phosphorylation Pregnancy prenatal exposure delayed effects Proto-Oncogene Proteins c-akt Rats Rats Wistar
Prenatal depression, fetal neurobehavior, and infant temperament
This article extends the research focusing on the early origins of psychopathology into the prenatal period, by exploring the association between maternal prenatal depression and offspring (fetal and infant) neurobehavior. The...
Obesogenic diet in mice compromises maternal metabolic physiology and lactation ability leading to reductions in neonatal viability.
Samantha C Lean, Alejandro A Candia, Edina Gulacsi, Giselle CL Lee, Amanda N Sferruzzi-Perri
Aug 04, 2022
Nutrition in early life and age-associated diseases.
Age-associated disease developmental programming MECHANISM Oxidative Stress Sub-optimal nutrition aging Animals Cardiovascular Diseases Cellular Senescence Chronic Disease Diabetes mellitus Type 2 Epigenesis Genetic Female Humans Models Animal Nutritional Status obesity Pregnancy prenatal exposure delayed effects
Association of preeclampsia with anthropometric measures and blood pressure in Indian children.
Karuna Randhir, Hemlata Pisal, Vrushali Kadam, Amrita Khaire-Ghadge, Nandini Malshe, Ruma Deshpande, Sonali Palkar, Sanjay Lalwani, Kalyanaraman Kumaran, Chittaranjan Yajnik, Clive Osmond, Caroline Fall, Sadhana Joshi
May 05, 2020
BACKGROUND AND OBJECTIVE: Birth weight and post-natal growth are important predictors of adult health. Preeclampsia (PE) is associated with low birth weight and may have long term effects on the health of the children. The...
|
|< |
< |
1 |