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Transcriptome Pathway Analysis of Pathological and Physiological Aldosterone-Producing Human Tissues.
Junhua Zhou, Brian Lam, Sudeshna G Neogi, Giles SH Yeo, Elena AB Azizan, Morris J Brown
Aug 16, 2017
Primary aldosteronism is present in ≈10% of hypertensives. We previously performed a microarray assay on aldosterone-producing adenomas and their paired zona glomerulosa and fasciculata. Confirmation of top genes validated the...
aldosterone Gene Ontology primary hyperaldosteronism Zona Fasciculata zona glomerulosa Adenoma Adrenal Cortex aldosterone G Protein-Coupled Inwardly-Rectifying Potassium Channels Gene Expression Profiling Gene Expression Regulation Humans hyperaldosteronism Pheochromocytoma Sampling Studies Transcription Factors Up-Regulation Wnt Signaling Pathway Zona Fasciculata zona glomerulosa