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Results: 4
Global reorganisation of $\textit{cis}$-regulatory units upon lineage commitment of human embryonic stem cells
P Freire-Pritchett, S Schoenfelder, C Várnai, SW Wingett, J Cairns, AJ Collier, R García-Vílchez, M Furlan-Magaril, CS Osborne, P Fraser, PJ Rugg-Gunn, M Spivakov
Jun 15, 2017
Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.
Biola M Javierre, Oliver S Burren, Steven P Wilder, Roman Kreuzhuber, Steven M Hill, Sven Sewitz, Jonathan Cairns, Steven W Wingett, Csilla Várnai, Michiel J Thiecke, Frances Burden, Samantha Farrow, Antony J Cutler, Karola Rehnström, Kate Downes, Luigi Grassi, Myrto Kostadima, Paula Freire-Pritchett, Fan Wang, BLUEPRINT Consortium, Hendrik G Stunnenberg, John A Todd, Daniel R Zerbino, Oliver Stegle, Willem H Ouwehand, Mattia Frontini, Chris Wallace, Mikhail Spivakov, Peter Fraser
Nov 18, 2016
chromosome conformation Disease gene prioritization Gene regulation non-coding genetic variation promoter capture Hi-C Blood Cells Cell Lineage Cell Separation Chromatin Disease Enhancer Elements Genetic Epigenomics Genetic Predisposition to Disease Genome-Wide Association Study Hematopoiesis Humans Polymorphism Single Nucleotide Promoter Regions Genetic Quantitative Trait Loci
Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition.
Clara Lopes Novo, Biola-Maria Javierre, Jonathan Cairns, Anne Segonds-Pichon, Steven W Wingett, Paula Freire-Pritchett, Mayra Furlan-Magaril, Stefan Schoenfelder, Peter Fraser, Peter J Rugg-Gunn
May 10, 2018
chromatin looping DIFFERENTIATION epigenetics Gene regulation genome organization Pluripotency promoter capture Hi-C Animals Cell Differentiation Enhancer Elements Genetic Gene Regulatory Networks Germ Layers Mice Mouse embryonic stem cells Nanog Homeobox Protein Pluripotent Stem Cells Promoter Regions Genetic Protein Binding
Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters
Biola M Javierre, Oliver S Burren, Steven P Wilder, Roman Kreuzhuber, Steven M Hill, Sven Sewitz, Jonathan Cairns, Steven W Wingett, Csilla Várnai, Michiel J Thiecke, Frances Burden, Samantha Farrow, Antony J Cutler, Karola Rehnstrom, Kate Downes, Luigi Grassi, Myrto Kostadima, Paula Freire-Pritchett, Fan Wang, BLUEPRINT Consortium The, Hendrik G Stunnenberg, John A Todd, Daniel R Zerbino, Oliver Stegle, Willem Hendrik Ouwehand, Mattia Frontini, Chris Wallace, Mikhail Spivakov, Peter Fraser
Aug 16, 2017
This is the final version of the article. It first appeared from Elsevier (Cell Press) via https://doi.org/10.1016/j.cell.2016.09.037
Gene regulation chromosome conformation promoter capture Hi-C non-coding genetic variation Disease gene prioritization
Published by: Cell