Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma.
Allison N Lau,
Zhaoqi Li,
Laura V Danai,
Anna M Westermark,
Alicia M Darnell,
Raphael Ferreira,
Vasilena Gocheva,
Sharanya Sivanand,
Evan C Lien,
Kiera M Sapp,
Jared R Mayers,
Giulia Biffi,
Christopher R Chin,
Shawn M Davidson,
David A Tuveson,
Tyler Jacks,
Nicholas J Matheson,
Omer Yilmaz,
Matthew G Vander Heiden
Oct 02, 2020
Tumors are composed of many different cell types including cancer cells, fibroblasts, and immune cells. Dissecting functional metabolic differences between cell types within a mixed population can be challenging due to the rapid...