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Cover Image for Gold(I)-catalysed synthesis of a furan analogue of thiamine pyrophosphate.

Gold(I)-catalysed synthesis of a furan analogue of thiamine pyrophosphate.

Amjid Iqbal, El-Habib Sahraoui, Finian J Leeper

Oct 17, 2014

furan synthesis gold-catalysed cyclisation pyruvate decarboxylase thiamine diphosphate

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Cover Image for (13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo.

(13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo.

Piotr Dzien, Sui-Seng Tee, Mikko I Kettunen, Scott K Lyons, Timothy J Larkin, Kerstin N Timm, De-En Hu, Alan Wright, Tiago B Rodrigues, Eva M Serrao, Irene Marco-Rius, Elizabeth Mannion, Paula D'Santos, Brett WC Kennedy, Kevin M Brindle

Aug 06, 2015

Zymomonas mobilis pyruvate decarboxylase hyperpolarized [1-13C] pyruvate reporter genes Animals Carbon-13 Magnetic Resonance Spectroscopy Enzyme Activation Female Genes Reporter HEK293 Cells Humans Magnetic Resonance Imaging Mice Mice SCID Molecular Imaging pyruvate decarboxylase Pyruvic Acid Recombinant Proteins Reproducibility of Results Sensitivity and Specificity Tissue Distribution Zymomonas

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