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Weight loss, insulin resistance, and study design confound results in a meta-analysis of animal models of fatty liver.
Harriet Hunter, Dana de Gracia Hahn, Amedine Duret, Yu Ri Im, Qinrong Cheah, Jiawen Dong, Madison Fairey, Clarissa Hjalmarsson, Alice Li, Hong Kai Lim, Lorcán McKeown, Claudia-Gabriela Mitrofan, Raunak Rao, Mrudula Utukuri, Ian A Rowe, Jake Mann
Oct 19, 2020
Weight loss, insulin resistance, and study design confound results in a meta-analysis of animal models of fatty liver
Harriet Hunter, Dana de Gracia Hahn, Amedine Duret, Yu Ri Im, Qinrong Cheah, Jiawen Dong, Madison Fairey, Clarissa Hjalmarsson, Alice Li, Hong Kai Lim, Lorcan McKeown, Claudia-Gabriela Mitrofan, Raunak Rao, Mrudula Utukuri, Ian A Rowe, Jake P Mann
Nov 09, 2020
The classical drug development pipeline necessitates studies using animal models of human disease to gauge future efficacy in humans, however there is a low conversion rate from success in animals to humans. Non-alcoholic fatty...