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Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells.
Mari-Liis Kauts, Bianca De Leo, Carmen Rodríguez-Seoane, Roger Ronn, Fokion Glykofrydis, Antonio Maglitto, Polynikis Kaimakis, Margarita Basi, Helen Taylor, Lesley Forrester, Adam C Wilkinson, Berthold Göttgens, Philippa Saunders, Elaine Dzierzak
Nov 16, 2018
Mast cells are tissue-resident immune cells. Their overgrowth/overactivation results in a range of common distressing, sometimes life-threatening disorders, including asthma, psoriasis, anaphylaxis, and mastocytosis. Currently...
ESC GATA2 Venus reporter DIFFERENTIATION iPSC immune effectors innate immune cells Mast Cells rapid protocol Stem Cells Animals Cell Culture Techniques Cell Differentiation Cells Cultured GATA2 Transcription Factor Genes Reporter Humans Mast Cells Mice Mouse embryonic stem cells Peptide Hydrolases Phenotype Pluripotent Stem Cells Receptors Cell Surface