Novel and Rare Fusion Transcripts Involving Transcription Factors and Tumor Suppressor Genes in Acute Myeloid Leukemia
Padella,
Simonetti,
Paciello,
Giotopoulos,
Baldazzi,
Righi,
Ghetti,
Stengel,
Guadagnuolo,
De Tommaso,
Papayannidis,
Robustelli,
Franchini,
Rorà,
Ferrari,
Fontana,
Bruno,
Ottaviani,
Soverini,
Storlazzi,
Haferlach,
Sabattini,
Testoni,
Iacobucci,
Huntly,
Ficarra,
Martinelli
Dec 06, 2019
Approximately 18% of acute myeloid leukemia (AML) cases express a fusion transcript. However, few fusions are recurrent across AML and the identification of these rare chimeras is of interest to characterize AML patients. Here...