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Pathophysiological Relevance of Renal Medullary Conditions on the Behaviour of Red Cells From Patients With Sickle Cell Anaemia
David C.-Y. Lu, Rasiqh Wadud, Anke Hannemann, David C. Rees, John N. Brewin, John Stanley Gibson
Apr 02, 2021
Red cells from patients with sickle cell anaemia (SCA) contain the abnormal haemoglobin HbS. Under hypoxic conditions, HbS polymerises and causes red cell sickling, a rise in intracellular Ca2+ and exposure of phosphatidylserine...
Identification of Structural and Molecular Signatures Mediating Adaptive Changes in the Mouse Kidney in Response to Pregnancy.
Jorge Lopez-Tello, Maria Angeles Jimenez-Martinez, Esteban Salazar-Petres, Ritik Patel, Amy L George, Richard G Kay, Amanda N Sferruzzi-Perri
Jul 10, 2022
Pregnancy is characterized by adaptations in the function of several maternal body systems that ensure the development of the fetus whilst maintaining health of the mother. The renal system is responsible for water and...