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Response-adaptive randomisation (RAR) can considerably improve the chances of a successful treatment outcome for patients in a clinical trial by skewing the allocation probability towards better performing treatments as data...

Clinical Trials power randomisation test response-adaptive randomisation Type I error Humans Patient Selection Randomized Controlled Trials as Topic Standard of Care Time Factors Treatment Outcome

Group sequential Phase III trial designs enable early stopping for positive or negative study outcomes. Response-adaptive randomisation can be included in such designs with the sampling ratio in each group of subjects...

group sequential test inferior treatment number response-adaptive randomisation /dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/2600/2600 name=General Mathematics /dk/atira/pure/subjectarea/asjc/1800/1804 name=Statistics, Probability and Uncertainty

Group sequential Phase III trial designs enable early stopping for positive or negative study outcomes. Response-adaptive randomisation can be included in such designs with the sampling ratio in each group of subjects...

group sequential test inferior treatment number response-adaptive randomisation /dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/2600/2600 name=General Mathematics /dk/atira/pure/subjectarea/asjc/1800/1804 name=Statistics, Probability and Uncertainty