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Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort.
Jingmei Li, Wei Xiong Wen, Martin Eklund, Anders Kvist, Mikael Eriksson, Helene Nordahl Christensen, Astrid Torstensson, Svetlana Bajalica-Lagercrantz, Alison M Dunning, Brennan Decker, Jamie Allen, Craig Luccarini, Karen Pooley, Jacques Simard, Leila Dorling, Douglas F Easton, Soo-Hwang Teo, Per Hall, Åke Borg, Henrik Grönberg, Kamila Czene
Oct 03, 2018
Breast cancer patients with BRCA1/2-driven tumors may benefit from targeted therapy. It is not clear whether current BRCA screening guidelines are effective at identifying these patients. The purpose of our study was to evaluate...