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Cover Image for Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds View Article
Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds
Jennifer A. Macdonald, John L. Chen, Masami Masuda-Suzukake, Manuel Schweighauser, Zane Jaunmuktane, Thomas Warner, Janice L. Holton, Annabelle Grossman, Richard Berks, Isabelle Lavenir, Michel Goedert
Dec 22, 2021
Abstract: Peripheral administration (oral, intranasal, intraperitoneal, intravenous) of assembled A53T α-synuclein induced synucleinopathy in heterozygous mice transgenic for human mutant A53T α-synuclein (line M83). The same...
Research α-synuclein Multiple System Atrophy seeded assembly neurodegeneration Microglia
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Cover Image for Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds. View Article
Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds.
Jennifer A Macdonald, John L Chen, Masami Masuda-Suzukake, Manuel Schweighauser, Zane Jaunmuktane, Thomas Warner, Janice L Holton, Annabelle Grossman, Richard Berks, Isabelle Lavenir, Michel Goedert
Nov 24, 2021
Peripheral administration (oral, intranasal, intraperitoneal, intravenous) of assembled A53T α-synuclein induced synucleinopathy in heterozygous mice transgenic for human mutant A53T α-synuclein (line M83). The same was the case...
Research α-synuclein Multiple System Atrophy seeded assembly neurodegeneration Microglia
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Cover Image for Programming the Nucleation of DNA Brick Self-Assembly with a Seeding Strand. View Article
Programming the Nucleation of DNA Brick Self-Assembly with a Seeding Strand.
Yingwei Zhang, Aleks Reinhardt, Pengfei Wang, Jie Song, Yonggang Ke
Feb 12, 2020
DNA bricks DNA nanotechnology controlled nucleation seeded assembly Self-assembly
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Cover Image for Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds. View Article
Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds.
Jennifer A Macdonald, John L Chen, Masami Masuda-Suzukake, Manuel Schweighauser, Zane Jaunmuktane, Thomas Warner, Janice L Holton, Annabelle Grossman, Richard Berks, Isabelle Lavenir, Michel Goedert
Jan 05, 2022
Peripheral administration (oral, intranasal, intraperitoneal, intravenous) of assembled A53T α-synuclein induced synucleinopathy in heterozygous mice transgenic for human mutant A53T α-synuclein (line M83). The same was the case...
Microglia Multiple System Atrophy neurodegeneration seeded assembly α-synuclein Aged Animals Animals Genetically Modified Hindlimb Humans Immunohistochemistry Male Mice Neurologic Mutants Microglia Motor Neurons MOVEMENT DISORDERS Multiple System Atrophy Mutation Neurodegenerative Diseases Neurons Paralysis ALPHA-SYNUCLEIN
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