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Metabolic regulation of pluripotency and germ cell fate through α-ketoglutarate.
Julia Tischler, Wolfram H Gruhn, John Reid, Edward Allgeyer, Florian Buettner, Carsten Marr, Fabian Theis, Ben D Simons, Lorenz Wernisch, M Azim Surani
Nov 16, 2018
cell state transitions Germ Cells metabolism pseudotime analysis single‐cell analysis Animals Cell Differentiation Cells Cultured Embryo Mammalian Embryonic Stem Cells Epigenesis Genetic Female Gene Expression Regulation Developmental Germ Cells Ketoglutaric Acids Male Metabolic Networks and Pathways Mice Mice Inbred C57BL Mice Transgenic Pluripotent Stem Cells