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Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis
Md Saiful Islam, Steven W Hardwick, Laura Quell, Svetlana Durica‐Mitic, Dimitri Y Chirgadze, Boris Görke, Ben F Luisi
Dec 12, 2022
Biogenesis of the essential precursor of the bacterial cell envelope, glucosamine‐6‐phosphate (GlcN6P), is controlled by intricate post‐transcriptional networks mediated by GlmZ, a small regulatory RNA (sRNA). GlmZ stimulates...
Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E.
RNA degradation RNA processing RNA structure RNA-mediated regulation RNase E protein-RNA interactions protein-RNA structure small regulatory RNA Amino Acid Sequence Catalysis Endoribonucleases Escherichia coli Escherichia coli Proteins Gene Expression Regulation Bacterial Protein Subunits RNA RNA Bacterial Sequence Alignment Substrate Specificity
A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation.
Tom Dendooven, Dhriti Sinha, Alzbeta Roeselová, Todd A Cameron, Nicholas R De Lay, Ben F Luisi, Katarzyna J Bandyra
May 28, 2021
Polynucleotide phosphorylase (PNPase) is an ancient exoribonuclease conserved in the course of evolution and is found in species as diverse as bacteria and humans. Paradoxically, Escherichia coli PNPase can act not only as an...
Hfq RNA chaperone cryoEM Gene Silencing polynucleotide phosphorylase Ribonuclease ribonucleoprotein complex riboregulation small regulatory RNA Catalytic Domain Endoribonucleases Escherichia coli Escherichia coli Proteins Exoribonucleases Gene Expression Regulation Bacterial Host Factor 1 Protein Molecular Chaperones Polyribonucleotide Nucleotidyltransferase RNA Stability RNA Bacterial RNA Small Untranslated