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Tracking SARS-CoV-2 mutations and variants through the COG-UK-Mutation Explorer.
Derek W Wright, William T Harvey, Joseph Hughes, MacGregor Cox, Thomas P Peacock, Rachel Colquhoun, Ben Jackson, Richard Orton, Morten Nielsen, Nienyun Sharon Hsu, COVID-19 Genomics UK (COG-UK) Consortium, Ewan M Harrison, Thushan I de Silva, Andrew Rambaut, Sharon J Peacock, David L Robertson, Alessandro M Carabelli
Jun 07, 2022
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity.
Emma C Thomson, Laura E Rosen, James G Shepherd, Roberto Spreafico, Ana da Silva Filipe, Jason A Wojcechowskyj, Chris Davis, Luca Piccoli, David J Pascall, Josh Dillen, Spyros Lytras, Nadine Czudnochowski, Rajiv Shah, Marcel Meury, Natasha Jesudason, Anna de Marco, Kathy Li, Jessica Bassi, Aine O'Toole, Dora Pinto, Rachel M Colquhoun, Katja Culap, Ben Jackson, Fabrizia Zatta, Andrew Rambaut, Stefano Jaconi, Vattipally B Sreenu, Jay Nix, Ivy Zhang, Ruth F Jarrett, William G Glass, Martina Beltramello, Kyriaki Nomikou, Matteo Pizzuto, Lily Tong, Elisabetta Cameroni, Tristan I Croll, Natasha Johnson, Julia Di Iulio, Arthur Wickenhagen, Alessandro Ceschi, Aoife M Harbison, Daniel Mair, Paolo Ferrari, Katherine Smollett, Federica Sallusto, Stephen Carmichael, Christian Garzoni, Jenna Nichols, Massimo Galli, Joseph Hughes, Agostino Riva, Antonia Ho, Marco Schiuma, Malcolm G Semple, Peter JM Openshaw, Elisa Fadda, J Kenneth Baillie, John D Chodera, ISARIC4C investigators, COVID-19 Genomics UK (COG-UK) Consortium, Suzannah J Rihn, Samantha J Lycett, Herbert W Virgin, Amalio Telenti, Davide Corti, David L Robertson, Gyorgy Snell
Feb 05, 2021
covid-19 N439K SARS-CoV-2 spike monoclonal antibody escape Mutation Protein Structure receptor binding motif variant Angiotensin-Converting Enzyme 2 Antibodies Neutralizing Antibodies Viral covid-19 Genetic Fitness Humans Immune Evasion Mutation Phylogeny SARS-CoV-2 Spike Glycoprotein Coronavirus Virulence
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity.
Erik Volz, Verity Hill, John T McCrone, Anna Price, David Jorgensen, Áine O'Toole, Joel Southgate, Robert Johnson, Ben Jackson, Fabricia F Nascimento, Sara M Rey, Samuel M Nicholls, Rachel M Colquhoun, Ana da Silva Filipe, James Shepherd, David J Pascall, Rajiv Shah, Natasha Jesudason, Kathy Li, Ruth Jarrett, Nicole Pacchiarini, Matthew Bull, Lily Geidelberg, Igor Siveroni, COG-UK Consortium, Ian Goodfellow, Nicholas J Loman, Oliver G Pybus, David L Robertson, Emma C Thomson, Andrew Rambaut, Thomas R Connor
Jan 12, 2021
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection...