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Results: 1
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Treatment allocation strategies for umbrella trials in the presence of multiple biomarkers
Luke Ondijo Ouma
,
Michael J Grayling
,
Haiyan Zheng
,
James Wason
Nov 22, 2021
Umbrella trials are an innovative trial design where different treatments are matched with subtypes of a disease, with the matching typically based on a set of biomarkers. Consequently, when patients can be positive for more...
adaptive design
adaptive randomisation
constrained randomisation
patient allocation
Precision Medicine
stratified randomisation
Bayes Theorem
Biomarkers
Computer Simulation
Humans
Random Allocation
Research Design
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